Recent Publications
- Chang C, Ton-That HL, Osipiuk J, Joachimiak A, Das A, Ton-That H (2024). Molecular basis for dual functions in pilus assembly modulated by the lid of a pilus-specific sortase. Journal of Biological Chemistry, (In Press). DOI: 10.1016/j.jbc.2024.107329
- Britton TA, Wu C, Chen YW, Franklin D, Chen Y, Camacho MI, Luong TT, Das A, Ton-That H (2024). The respiratory enzyme complex Rnf is vital for metabolic adaptation and virulence in Fusobacterium nucleatum. mBio, 15(1):e0175123.
- Sue CK, Cheung NA, Mahoney BJ, McConnell SA, Scully JM, Fu JY, Chang C, Ton-That H, Loo JA, Clubb RT (2024). The basal and major pilins in the Corynebacterium diphtheriae SpaA pilus adopt similar structures that competitively react with the pilin polymerase. Biopolymers, 115(1):e23539.
- Reardon-Robinson M*, Nguyen MT*, Sanchez BC*, Osipiuk J, Rückert C, Chang C, Chen B, Nagveka R, Joachimiak A, Tauch A, Das A, and Ton-That H (2023). A cryptic thiol-disulfide oxidoreductase safeguards oxidative protein folding in Corynebacterium diphtheriae. Proc Natl Acad Sci U S A, 120(8):e2208675120
- Chen YW*, Camacho MI*, Chen Y, Bhat AH, Chang C, Peluso EA, Wittchen M, Tauch A, Wu C, Das A, and Ton-That H (2022). Genetic Determinants of Hydrogen Sulfide Biosynthesis in Fusobacterium nucleatum Are Required for Bacterial Fitness, Antibiotic Sensitivity, and Virulence. mBio, e0193622. doi: 10.1128/mbio.01936-22
- Ramirez NA*, Wu C*, Chang C, Siegel SD, Das A, and Ton-That H (2022). A conserved signal-peptidase antagonist modulates membrane homeostasis of actinobacterial sortase critical for surface morphogenesis. Proc Natl Acad Sci U S A, 119(28):e2203114119
- Kim S, Bando Y, Chang C, Kwon J, Tarverti B, Kim D, Lee SH, Ton-That H, Kim R, Nara PL, Park NH (2022). Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation. Int J Mol Med, 50(2):103. doi: 10.3892/ijmm.2022.5159
- Al Mamun AA, Wu C, Chang C, Sanchez BC, Das A, Ton-That H (2022). A cell wall anchored glycoprotein confers resistance to cation stress in Actinomyces oris biofilms. Molecular Oral Microbiology, DOI: 10.1111/omi.12365
- Scheible M, Nguyen CT, Luong TT, Lee JH, Chen YW, Chang C, Wittchen M, Camacho MI, Tiner BL, Wu C, Tauch, Das A, and Ton-That H (2022). The fused methionine sulfoxide reductase MsrAB promotes oxidative stress defense and bacterial virulence in Fusobacterium nucleatum. mBio, DOI: 10.1128/mbio.03022-21
- Wu C, Chen YW, Scheible M Chang C, Wittchen M, Lee JH, Luong TT, Tiner BL, Tauch A, Das A, and Ton-That H (2021). Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum. Proc Natl Acad Sci U S A, 118(23). doi: 10.1073/pnas.2006482118.
- Luong TT*, Nguyen MT*, Chen YW*, Chang C, Lee JH, Wittchen M, Ton-That HL, Cruz M, Garsin DA, Das A, Tauch A, and Ton-That H (2021). Ribonuclease J mediated mRNA turnover modulates cell shape, metabolism and virulence in Corynebacterium diphtheriae. Microorganisms, 14;9(2):389. doi: 10.3390/microorganisms9020389.
- Bhat AH*, Nguyen MT*, Das A, and Ton-That H (2021). Anchoring surface proteins to the bacterial cell wall by sortase enzymes: How it started and what we know now. Current Opinion in Microbiology, 118(12):e2019649118. doi: 10.1073/pnas.2019649118
*Equal Contribution